| Triple-phase VPA administration in Sprague-Dawley rats: A cost-effective ASD model unveiling the synaptic-mitochondrial-inflammatory axis as a therapeutic target |
Zhaoming Liu, Caixia Wu , Zuoxian Lin, Heying Li , Yujie Liu, Nouman Amjad, Muhammad Majid, Rajesh Basnet, Zhiyuan Li
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2025 |
Life sciences |
| Mutations in ClpC1 or ClpX subunit of caseinolytic protease confer resistance to ilamycins in mycobacteria |
Yamin Gao, Cuiting Fang, Biao Zhou, H M Adnan Hameed, Changli Sun, Xirong Tian, Jing He, Xingli Han, Han Zhang, Jun Li, Jianhua Ju, Xinwen Chen, Nanshan Zhong,Junying Ma, Xiaoli Xiong,Tianyu Zhang |
2025 |
Communications biology |
| RNA modification is the mark and strategy for host-microbe interactions |
Ye Tian, Xiaoyun Wang |
2025 |
Cellular and molecular life sciences |
| Transcriptome-wide regulation of folate on neural mRNA m(6)A methylome via carbon metabolism in Drosophila and mammals |
Anrui Liu, Zhengyi Hu, Zihe Xu, Sisi Liu, Yuting Jiao, Rui Li, Yi Lu, Meng Yang, Jia Huang, Chen Huang, Xiaoyun Wang |
2025 |
Communications biology |
| High-resolution mapping of single cells in spatial context |
Jincan Ke, Jian Xu, Jia Liu, Yumeng Yang, Chenkai Guo, Bingbing Xie, Guizhong Cui, Guangdun Peng, Shengbao Suo
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2025 |
Nature Communications |
| Structures and receptor binding activities of merbecovirus spike proteins reveal key signatures for human DPP4 adaptation |
Hang Yuan, Jingjing Wang , Yong Ma, Zimu Li, Xijie Gao, Gul Habib, Banghui Liu, Jing Chen, Jun He, Peng Zhou, Zheng-Li Shi, Xinwen Chen, Xiaoli Xiong
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2025 |
Science Advances |
| ScReNI: Single-cell Regulatory Network Inference Through Integrating scRNA-seq and scATAC-seq Data |
Xueli Xu, Yanran Liang, Miaoxiu Tang, Jiongliang Wang, Xi Wang, Yixue Li , Jie Wang
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2025 |
Genomics proteomics & bioinformatics |
| Copper ion-chelated supramolecular polymer/hyaluronic acid hydrogel promotes wound healing in diabetes |
Daoqiang Lu, Wenchong Yu , Danni Zhao, Fei Qi, Xiu Wang, Qiang Fu, Jie Li, Fang Yang, Riwang L, Xiaoxiao Wang, Haotian Lan, Jieyan Wang, Honglin Zhang, Dahai Liu, Jun Wang, Xiaodong Zhao
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2025 |
International journal of biological macromolecules |
| Discovery of a Potent, Selective, and Multiple His435 Mutation-Sensitive Thyroid Hormone Receptor beta Agonist |
Qiu Li, Benqiang Yao, Shiting Zhao, Zhou Lu, Xishan Wu, Zhifang Lu, Tong Wu, Junhua Li, Xiaoshan Chen, Zhiming Chen, Cheng Zhang, Donghai Wu, Yan Zhang, Qiuping Xiang, Yong Li, Yong Xu
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2025 |
Journal of medicinal chemistry |
| Reply: Considerations on the specific role of LHX2 in the process of hepatic stellate cells regulating hepatocyte function |
Jiawang Tao, Jie Wang
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2025 |
Hepatology |
| Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer |
Lingyan Zhou, Feixiang Bao, Jiajun Zheng, Yingzhe Ding, Jiahui Xiao, Jian Zhang, Yongpeng Qin, Liang Yang , Yi Wu, Qi Meng, Manjiao Lu, Qi Long, Lingli Hu, Chong Li, Haitao Wang, Shijuan Huang, Linpeng Li, Junwei Wang, Wuming Wang, Gang Lu, Wai-Yee Chan, Dajiang Qin, Gong Chen, Xingguo Liu
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2025 |
Molecular psychiatry |
| A cocktail hydrogel promoting the functional interneurons regeneration of human neural progenitor cells for brain injury therapy |
Di Zhang, Jun Chen, Huaisong Lin, Min Zhou, Jinfei Hou, Wei Sun, Qi Xing, Wenhao Huang, Yanqi Zhang, Yiping Guo, Chunhua Liu, Aiping Lin, Cong Zhang, Yuhua Huang, Li-En Tao, Bowen Xie, Jian Zhang, Qianyu Chen, Yongli Shan, Yanling Zhu, Guangjin Pan, Lin-Ping Wu
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2025 |
Journal of Advanced Research |
| Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase |
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng |
2025 |
Advanced science(Weinheim) |
| beta-hydroxybutyrate enhances mitochondrial function via mitochondrial-derived vesicles |
Feixiang Bao, Dingxin Zeng, Jiahui Xiao, Lingyan Zhou, Xingguo Liu |
2025 |
Science bulletin(Beijing) |
| Function of hematopoiesis and bone marrow niche in inflammation and non-hematopoietic diseases |
Yu-Xiang Wang, Zhao-Hua Deng, Yu-Yan Li, Ke Bai, Jinjin Ma, Yang Liu, Qi Chen
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2025 |
Life medicine |
| Regiospecific 2,3-Dialkylindole Synthesis Enabled by Alkylpalladium 1,2-Migration to In Situ Formed Aldimine |
Sidi Cheng, Yingxiang Liang, Tao Zhang, Meiling Chen, Jing Li, Xiaohan Zhang, Shuang Luo, Qiang Zhu
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2025 |
Angewandte Chemie-International edition |
| DNMT1 inhibition reprograms T cells to NK-like cells with potent antitumor activity |
Yao Li, Jiongliang Wang , Linfu Zhou, Wenbin Gu, Le Qin, Dongdong Peng, Shanglin Li, Diwei Zheng, Qiting Wu, Youguo Long, Yao Yao, Shouheng Lin, Mingwei Sun, Xiaofei Zhang, Jie Wang, Pentao Liu, Xiangqian Kong, Peng Li
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2025 |
SCIENCE IMMUNOLOGY |
| CD4(+) anti-TGF-beta CAR T cells and CD8(+) conventional CAR T cells exhibit synergistic antitumor effects |
Diwei Zheng, Le Qin, Jiang Lv, Meihui Che, Bingjia He, Yongfang Zheng, Shouheng Lin, Yuekun Qi, Ming Li, Zhaoyang Tang, Bin-Chao Wang, Yi-Long Wu, Robert Weinkove, Georgia Carson, Yao Yao, Nathalie Wong, James Lau, Jean Paul Thiery, Dajiang Qin, Bin Pan, Kailin Xu, Zhenfeng Zhang, Peng Li
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2025 |
?Cell Reports Medicine |
| SARS-related coronavirus S-protein structures reveal synergistic RBM interactions underpinning high-affinity human ACE2 binding |
Jingjing Wang, Yong Ma, Zimu Li, Hang Yuan, Banghui Liu, Zexuan Li, Mengzhen Su, Gul Habib, Yutong Liu, Lutang Fu, Peiyi Wang, Mei Li, Jun He, Jing Chen, Peng Zhou, Zhengli Shi, Xinwen Chen, Xiaoli Xiong
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2025 |
Science Advances |
| Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses |
Lu Xue, Tiancai Chang, Jiacheng Gui, Zimu Li, Heyu Zhao, Binqian Zou, Junnan Lu, Mei Li, Xin Wen, Shenghua Gao, Peng Zhan, Lijun Rong, Liqiang Feng, Peng Gong, Jun He, Xinwen Chen, Xiaoli Xiong |
2025 |
Protein Cell |
| Dissecting the Spatial and Single-Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer |
Guangyu Zhang, Xin Zhang , Wenting Pan, Xizhao Chen, Lingfei Wan, Chunjie Liu, Yuting Yong, Yue Zhao, Shuli Sang, Lihua Zhang, Sheng Yao, Yushu Guo, Mingmei Wang, Xinhui Wang, Guangdun Peng, Xinlong Yan, Yanchun Wang, Min Zhang
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2025 |
Advanced science(Weinheim) |
| STING directly interacts with PAR to promote apoptosis upon acute ionizing radiation-mediated DNA damage |
Yirong Sun, Saba R Aliyari, Kislay Parvatiyar, Lulan Wan, Anjie Zhen, Wei Sun, Xiaobo Han, Adele Zhang, Ethan Kato, Helen Shi, Elena De Schutter, William H McBride, Samuel W French, Genhong Cheng
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2025 |
Cell Death and Differentiation |
| Learning Phenotype Associated Signature in Spatial Transcriptomics with PASSAGE |
Chen-Kai Guo, Chen-Rui Xia, Guangdun Peng, Zhi-Jie Cao, Ge Gao |
2025 |
Small Methods |
| An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape |
Weiqi Deng, Xuefeng Niu , Ping He, Qihong Yan, Huan Liang, Yongping Wang, Lishan Ning, Zihan Lin, Yudi Zhang, Xinwei Zhao, Liqiang Feng, Linbing Qu, Ling Chen
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2025 |
Frontiers in immunology |
| Capture primed pluripotency in guinea pig |
Jing Guo, Runxia Lin, Jinpeng Liu, Rongrong Liu, Shuyan Chen, Zhen Zhang, Yongzheng Yang, Haiyun Wang, Luqin Wang, Shengyong Yu, Chunhua Zhou, Lizhan Xiao, Rongping Luo, Jinjin Yu , Lihua Zeng, Xiaoli Zhang, Yusha Li, Haokaifeng Wu, Tao Wang , Yi Li, Manish Kumar, Ping Zhu, Jing Liu
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2025 |
Stem Cell Reports |
| Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy |
Wenjing Bai, Jinxin Xu, Wenbin Gu, Danyang Wang, Ying Cui, Weidong Rong, Xiaoan Du, Xiaoxia Li, Cuicui Xia, Qingqing Gan, Guantao He, Huahui Guo, Jinfeng Deng, Yuqiong Wu, Ray-Whay Chiu Yen, Srinivasan Yegnasubramanian, Scott B Rothbart, Cheng Luo, Linping Wu, Jinsong Liu, Stephen B Baylin, Xiangqian Kong |
2025 |
Nature Communications |
| Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer |
Hui Shen, Hongrui Xu, Weiqin Jin, Tianbang Wu, Jiankang Hu, Cheng Zhang, Zhixin Zhong, Junhua Li, Rui Mao, Sheng Zhang, Xiao Zhang, Xishan Wu, Jeff B Smaill, Jinxin Xu, Yan Zhang, Yong Xu |
2025 |
Journal of medicinal chemistry |
| Dual-nuclease single-cell lineage tracing by Cas9 and Cas12a |
Cheng Chen, Yuanxin Liao, Miao Zhu, Li Wang, Xinran Yu, Meishi Li, Guangdun Peng |
2025 |
Cell reports |
| Leveraging spatial multiomics to unravel tissue architecture in embryo development |
Fuqing Jiang, Haoxian Wang, Zhuxia Li, Guizhong Cui, Guangdun Peng |
2025 |
Trends in genetics |
| MSC-mediated mitochondrial transfer restores mitochondrial DNA and function in neural progenitor cells of Leber's hereditary optic neuropathy |
Rui Wang, Feixiang Bao, Manjiao Lu, Xiaoyun Jia, Jiahui Xiao, Yi Wu, Qingjiong Zhang, Xingguo Liu |
2024 |
Science China-Life Sciences |
